MAGIC EMBO | The GI Bleed Study
Project Summary
Acute non-variceal lower gastrointestinal (GI) bleeding is a common medical emergency associated with high hospitalisation rates and mortality of up to 10%. While transcatheter arterial embolisation is an established, minimally invasive alternative to surgery, there is a lack of risk stratification tools to guide patient selection, unlike the established pathways for endoscopy. This represents a significant clinical gap in optimising care for these critically ill patients.
This study aims to analyse the current practice of emergency embolisation for lower tract GI bleeding to better understand predictors of outcomes and improve emergency management.
Study Team
Deevia Kotecha. Chief Investigator. IR Specialty Registrar, Preston.
Indrajeet Mandal. IR Specialty Registrar, Oxford University Hospitals.
Noemi Cinti. Foundation Doctor, Wolverhampton.
Scott Griffiths. Radiology Specialty Registrar, Hull.
David Schramm. Foundation Doctor, Northampton.
Ganesh Vigneswaran. IR Consultant & Senior Lecturer, Southampton.
Paul Jenkins. IR Consultant, Plymouth.​
Dr Deevia Kotecha
Chief Investigator
Study Details
Primary Objective
To establish the rates of rebleeding, reintervention, embolisation failure, and complications following emergency embolisation.
Inclusion Criteria
Adult patients undergoing embolisation for non-variceal lower GI bleeding.
Sample Size
Expected sample size 800 across all sites
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Study Period
24 months
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Funding
This study is supported by a BSIR Research Grant, RCR Kodak Grant as well as the Guts UK charity.
Study Design
Multicentre retrospective study
Exclusion Criteria
Patients undergoing embolisation for upper GI bleeding, variceal bleeding or chronic GI bleeding.
Follow up Duration
6 months
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Ethical Approval
The study has obtained IRAS approval via University Hospitals Plymouth, and will be conduct according the ethical regulations.
Study Documents
Study
Protocol
RedCap Database
Registration Form
Guidance Document
COLLABORATORS SECTION
Registration Process
1
Site registration form
If you would like to register your centre, please email us. You will need to provide details about your local IR department's practice, as well as provide details of the study team at your site. A site study team consists of a supervising consultant (PI), and at least one trainee (associate PI).
2
Local Project Approval
Once you have filled in the site registration form, please email us to indicate your interest in taking part. The next step will be to register the study at your local site officially. This requires involvement of your R&D department, and possibly the Caldicott guardian.
3
Data Collection
Firstly, you will need to search your hospital's RIS/other system and identify all of the relevant cases. For each eligible case, you will need to collect datapoints form each one. All of the data will be uploaded directly to a central RedCap database. Please do NOT email us any data directly.
Frequently Asked Questions (FAQs)
Here we include details of some commonly asked questions about this project.